Electrochemical oxidation of anti-inflammatory drug meloxicam and its determination using boron doped diamond electrode
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F20%3A73603855" target="_blank" >RIV/61989592:15310/20:73603855 - isvavai.cz</a>
Alternative codes found
RIV/00216275:25310/20:39916369
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S1572665719310264" target="_blank" >https://www.sciencedirect.com/science/article/pii/S1572665719310264</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jelechem.2019.113758" target="_blank" >10.1016/j.jelechem.2019.113758</a>
Alternative languages
Result language
angličtina
Original language name
Electrochemical oxidation of anti-inflammatory drug meloxicam and its determination using boron doped diamond electrode
Original language description
Voltammetric behavior of a nonsteroidal anti-inflammatory drug meloxicam was firstly studied using boron doped diamond electrode (BDDE). Two irreversible anodic current peaks were observed in wide pH range at potentials +900 mV and +1400 mV vs. saturated silver-silver chloride electrode. Mechanism of the electrochemical oxidation was proposed and confirmed using high performance liquid chromatography/mass spectrometry analysis of electrolyzed meloxicam solutions. Subsequently, an analytical method for meloxicam determination was developed using differential pulse voltammetry in connection with BDDE. This method provides low limit of detection (5.9 x 10(-8) mol L-1) and wide linear dynamic range (2.5 x 10(-7)-8.5 x 10(-5) mol L-1). Finally, model solutions as well as pharmaceutical preparations were successfully analyzed, and the meloxicam content was determined.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10406 - Analytical chemistry
Result continuities
Project
<a href="/en/project/GA17-03868S" target="_blank" >GA17-03868S: New Methods of Electrochemical Monitoring of Biologically Active Organic Compounds in Environmental, Biological and Food Matrices</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
ISSN
1572-6657
e-ISSN
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Volume of the periodical
858
Issue of the periodical within the volume
FEB
Country of publishing house
CH - SWITZERLAND
Number of pages
9
Pages from-to
"113758-1"-"113758-9"
UT code for WoS article
000515205600004
EID of the result in the Scopus database
2-s2.0-85076893090