On the label-free analysis of white blood cells by holographic quantitative phase imaging flow cytometry
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F24%3A73627238" target="_blank" >RIV/61989592:15310/24:73627238 - isvavai.cz</a>
Result on the web
<a href="https://obd.upol.cz/id_publ/333207125" target="_blank" >https://obd.upol.cz/id_publ/333207125</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1364/JOSAA.536841" target="_blank" >10.1364/JOSAA.536841</a>
Alternative languages
Result language
angličtina
Original language name
On the label-free analysis of white blood cells by holographic quantitative phase imaging flow cytometry
Original language description
This study presents an innovative methodology to analyze a blood sample from a healthy donor, providing a quantitative characterization of white blood cells (WBCs). It aims to evaluate the effectiveness of holographic quantitative phase imaging (QPI) flow cytometry (FC) in examining phase-contrast maps at the cellular level, thereby enabling the identification and classification of granulocyte types. Additionally, we demonstrate that an unsupervised method can differentiate granulocyte sub-types, i.e., neutrophils and eosinophils. The results instill strong confidence in the potential future use of QPI FC for liquid biopsies and/or for assessing the heterogeneity of WBCs and, more broadly, to facilitate label-free blood tests.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10306 - Optics (including laser optics and quantum optics)
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION
ISSN
1084-7529
e-ISSN
1520-8532
Volume of the periodical
41
Issue of the periodical within the volume
12
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
"2421 "- 2429
UT code for WoS article
001368000400006
EID of the result in the Scopus database
2-s2.0-85211455082