Analysis of micro RNAs expression in cell lines derieved from prostate carcinoma
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F12%3A00190269" target="_blank" >RIV/62156489:43210/12:00190269 - isvavai.cz</a>
Result on the web
—
DOI - Digital Object Identifier
—
Alternative languages
Result language
angličtina
Original language name
Analysis of micro RNAs expression in cell lines derieved from prostate carcinoma
Original language description
MiRNAs constitute a large class of single-stranded RNA molecules of 19 to 25 nucleotides that are involved in post-transcriptional gene silencing. MiRNAs not only regulate various developmental and physiologic processes but also are involved in cancer development and can play a role as an important biomarkers. The aim of this study was to determinate the expression levels of selected miRNA in the non-tumor PNT1A line in comparison with tumor lines 22Rv1, PC-3, and LNCaP. We used the TaqMan Gene Expression Assays and quantitative RT-PCR. We observed significantly higher (p<0.01) expression of miRNA 23a in all tumor lines compared to non-tumor PNT1A. Significantly higher (p<0.01) expression of miRNA 224 in 22Rv1 line compared to others and significantlyhigher (p<0.01) expression of miRNA 375 in all tumor lines in comparison with non-tumor PNT1A
Czech name
—
Czech description
—
Classification
Type
D - Article in proceedings
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
—
Result continuities
Project
<a href="/en/project/GAP102%2F11%2F1068" target="_blank" >GAP102/11/1068: Nano-Electro-Bio-Tools for Biochemical and Molecularly-Biological Studies of Eukaryotic Cells (NanoBioTECell)</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
XII. Pracovní setkání fyzikálních chemiků a elektrochemiků
ISBN
978-80-7375-618-5
ISSN
—
e-ISSN
—
Number of pages
3
Pages from-to
77-79
Publisher name
Mendelova univerzita v Brně
Place of publication
Mendelova univerzita v Brně
Event location
Brno, Česká republika
Event date
Jan 1, 2012
Type of event by nationality
CST - Celostátní akce
UT code for WoS article
—