Investigating the influence of taurine on thiol antioxidant status in Wistar rats with a multi-analytical approach

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F14%3A00217718" target="_blank" >RIV/62156489:43210/14:00217718 - isvavai.cz</a>
Alternative codes found
RIV/60162694:G44__/14:43875120 RIV/62157124:16270/14:43872978 RIV/00216305:26220/14:PU112438
Result on the web
<a href="http://www.sciencedirect.com/science/article/pii/S1214021X13000094" target="_blank" >http://www.sciencedirect.com/science/article/pii/S1214021X13000094</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jab.2013.01.002" target="_blank" >10.1016/j.jab.2013.01.002</a>

Result language
angličtina
Original language name
Investigating the influence of taurine on thiol antioxidant status in Wistar rats with a multi-analytical approach
Original language description
Taurine (2-aminoethanesulfonic acid) is an organic acid widely distributed in animal tissues. It is involved in many physiological processes. Thus, it is widely discussed especially due to its antioxidant properties. In this study, we focused on the effect of taurine supplementation on the concentration of antioxidants in blood plasma and erythrocytes of Wistar rats. Taurine was applied in feed mixture in the dosage of 0, 1, 250, 500, 750, 1000, 1500, 2000, 2500, 3000, 3500 and 4000 mg/kg. We monitoredboth enzymatic and non-enzymatic antioxidants -- glutathione peroxidase, glutathione reductase, and superoxide dismutase and reduced/oxidized glutathione and metallothionein. Using three different methods 2,20-azino-bis(3-ethylbenzothiazoline-6-sulfonicacid (ABTS), Ferric Reducing Antioxidant Power (FRAP) and free radicals, we determined antioxidant capacity. In addition, we monitored levels of uric acid and glucose. Our results revealed significant changes in both enzymatic and non-enz
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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