Effect of Lipopolysaccharide and Muramyl Dipeptide on the Inflammatory Cytokine Production throughout Inflammatory Response of Bovine Mammary Gland

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F18%3A43909254" target="_blank" >RIV/62156489:43210/18:43909254 - isvavai.cz</a>
Result on the web
<a href="https://www.medwelljournals.com/abstract/?doi=javaa.2018.100.103" target="_blank" >https://www.medwelljournals.com/abstract/?doi=javaa.2018.100.103</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Effect of Lipopolysaccharide and Muramyl Dipeptide on the Inflammatory Cytokine Production throughout Inflammatory Response of Bovine Mammary Gland
Original language description
The objective of this study was to get a better knowledge of inflammatory cytokine production (TNF-α, IL-4, IL-10, and TGFβ1) throughout inflammatory response of bovine mammary gland caused by bacterial toxin lipopolysacharide (LPS) and muramyl dipeptide as a structural unit of peptidoglycan (MDP). In the experiments, there were used LPS and MDP at the specified concentrations (5 µg and 500 µg, respectively). The inflammatory response was analyzed at selected time points (24, 48, 72, and 168 h) following stimulation of the mammary glands. As a control, the same volumes of physiological solution was used. The mammary gland lavages were collected from the 8 clinically healthy virgin Holstein x Czech Pied heifers and the concentrations of the cytokines were analyzed by an ELISA method.
Czech name
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Czech description
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Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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