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Effect of Lipopolysaccharide and Muramyl Dipeptide on the Inflammatory Cytokine Production throughout Inflammatory Response of Bovine Mammary Gland

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F18%3A43909254" target="_blank" >RIV/62156489:43210/18:43909254 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.medwelljournals.com/abstract/?doi=javaa.2018.100.103" target="_blank" >https://www.medwelljournals.com/abstract/?doi=javaa.2018.100.103</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Effect of Lipopolysaccharide and Muramyl Dipeptide on the Inflammatory Cytokine Production throughout Inflammatory Response of Bovine Mammary Gland

  • Original language description

    The objective of this study was to get a better knowledge of inflammatory cytokine production (TNF-α, IL-4, IL-10, and TGFβ1) throughout inflammatory response of bovine mammary gland caused by bacterial toxin lipopolysacharide (LPS) and muramyl dipeptide as a structural unit of peptidoglycan (MDP). In the experiments, there were used LPS and MDP at the specified concentrations (5 µg and 500 µg, respectively). The inflammatory response was analyzed at selected time points (24, 48, 72, and 168 h) following stimulation of the mammary glands. As a control, the same volumes of physiological solution was used. The mammary gland lavages were collected from the 8 clinically healthy virgin Holstein x Czech Pied heifers and the concentrations of the cytokines were analyzed by an ELISA method.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>ost</sub> - Miscellaneous article in a specialist periodical

  • CEP classification

  • OECD FORD branch

    40301 - Veterinary science

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Animal and Veterinary Advances

  • ISSN

    1680-5593

  • e-ISSN

  • Volume of the periodical

    17

  • Issue of the periodical within the volume

    5

  • Country of publishing house

    PK - PAKISTAN

  • Number of pages

    4

  • Pages from-to

    100-103

  • UT code for WoS article

  • EID of the result in the Scopus database