Transforming growth factor beta 1 production during inflammatory response of mammary gland induced by peptidoglycan
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F18%3A43914678" target="_blank" >RIV/62156489:43210/18:43914678 - isvavai.cz</a>
Result on the web
<a href="https://mnet.mendelu.cz/mendelnet2018/mnet_2018_full.pdf" target="_blank" >https://mnet.mendelu.cz/mendelnet2018/mnet_2018_full.pdf</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Transforming growth factor beta 1 production during inflammatory response of mammary gland induced by peptidoglycan
Original language description
Intramammary infection promotes increase in production of two isoforms of transforming growth factor beta (TGF-β) which are TGF-β1 and TGF-β2. The aim of this study was to investigate the production of TGF-β1 during an inflammatory response of bovine mammary gland induced by peptidoglycan of S. aureus. The experiment was performed on 32 mammary glands of 8 healthy virgin crossbred heifers. Lavages of the mammary glands were analysed using sandwich ELISA technique. The results showed that stimulation with peptidoglycan led to a significant increase in the concentration of TGF-β1. We suggest that peptidoglycan of S. aureus stimulated immune cells to production of TGF-β1 at least in three days following stimulation of mammary glands. TGF-β1 is one of the most important cytokines in restoring the mammary gland within mastitis and stimulation with peptidoglycan helped us see the heifer's mammary gland immune response.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
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OECD FORD branch
40301 - Veterinary science
Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
MendelNet 2018: Proceedings of International PhD Students Conference
ISBN
978-80-7509-597-8
ISSN
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e-ISSN
neuvedeno
Number of pages
4
Pages from-to
366-369
Publisher name
Mendelova univerzita v Brně
Place of publication
Brno
Event location
Brno
Event date
Nov 7, 2018
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
000462205300068