Variability of Selected Genes in Relation to the Parameters of Bones in Laying Hens: A Pilot Study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F19%3A43916667" target="_blank" >RIV/62156489:43210/19:43916667 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.15414/jmbfs.2019.9.special.449-452" target="_blank" >http://dx.doi.org/10.15414/jmbfs.2019.9.special.449-452</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.15414/jmbfs.2019.9.special.449-452" target="_blank" >10.15414/jmbfs.2019.9.special.449-452</a>
Alternative languages
Result language
angličtina
Original language name
Variability of Selected Genes in Relation to the Parameters of Bones in Laying Hens: A Pilot Study
Original language description
The aim of the present study was to screen potential key genes associated with osteoporosis in laying hens. We performed association analysis of single nucleotide polymorphisms of selected genes encoding non-collagenous proteins (IBSP, SPP1, FN1, MEPE, DCN, THBS2) with parameters of bones in a group of ISA Brown laying hens. The surveyed parameters were bone breaking strength, length, width and bone mass. In this pilot study, nineteen samples for genes encoding non-collagenous proteins were tested. The polymorphisms were detected using PCR method and sequencing. Seven polymorphisms have been discovered in genes encoding non-collagenous proteins in the genes FN1 (c.7413A>G, c.7440+57G>A, c.7440+105G>A, c.7441-71T>C), DCN (c.158C>T) and SPP1 (c.362+117G>C, c.363-88G>C), of which two of these polymorphisms were synonymous and five were in the intron. Despite the position of the found polymorphisms, no association with the mechanical parameters of the bones were found.
Czech name
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Czech description
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Classification
Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
40203 - Husbandry
Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Microbiology, Biotechnology and Food Science
ISSN
1338-5178
e-ISSN
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Volume of the periodical
9
Issue of the periodical within the volume
Special Issue
Country of publishing house
SK - SLOVAKIA
Number of pages
4
Pages from-to
449-452
UT code for WoS article
000500544500020
EID of the result in the Scopus database
2-s2.0-85083699043