Microfluidics chips fabrication techniques comparison

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F24%3A43926127" target="_blank" >RIV/62156489:43210/24:43926127 - isvavai.cz</a>

Alternative codes found

RIV/00216305:26220/24:PU154922

Result on the web

<a href="https://doi.org/10.1038/s41598-024-80332-2" target="_blank" >https://doi.org/10.1038/s41598-024-80332-2</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1038/s41598-024-80332-2" target="_blank" >10.1038/s41598-024-80332-2</a>

Result language

angličtina

Original language name

Microfluidics chips fabrication techniques comparison

Original language description

This study investigates various microfluidic chip fabrication techniques, highlighting their applicability and limitations in the context of urgent diagnostic needs showcased by the COVID-19 pandemic. Through a detailed examination of methods such as computer numerical control milling of a polymethyl methacrylate, soft lithography for polydimethylsiloxane-based devices, xurography for glass-glass chips, and micromachining-based silicon-glass chips, we analyze each technique&apos;s strengths and trade-offs. Hence, we discuss the fabrication complexity and chip thermal properties, such as heating and cooling rates, which are essential features of chip utilization for a polymerase chain reaction. Our comparative analysis reveals critical insights into material challenges, design flexibility, and cost-efficiency, aiming to guide the development of robust and reliable microfluidic devices for healthcare and research. This work underscores the importance of selecting appropriate fabrication methods to optimize device functionality, durability, and production efficiency.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10406 - Analytical chemistry

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Scientific Reports

ISSN

2045-2322

e-ISSN

2045-2322

Volume of the periodical

14

Issue of the periodical within the volume

20 November

Country of publishing house

GB - UNITED KINGDOM

Number of pages

13

Pages from-to

28793

UT code for WoS article

001361297900018

EID of the result in the Scopus database

2-s2.0-85209760709