Analysis of selected polymorphisms found within genes involved in bone metabolism signaling pathways with morphometric parameters of bone tissue in broilers

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F25%3A43927236" target="_blank" >RIV/62156489:43210/25:43927236 - isvavai.cz</a>

Result on the web

<a href="https://doi.org/10.55251/jmbfs.11735" target="_blank" >https://doi.org/10.55251/jmbfs.11735</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.55251/jmbfs.11735" target="_blank" >10.55251/jmbfs.11735</a>

Result language

angličtina

Original language name

Analysis of selected polymorphisms found within genes involved in bone metabolism signaling pathways with morphometric parameters of bone tissue in broilers

Original language description

The constant improvement of genetic tools, mainly due to the influence of genetic selection, leads to a permanent increase in the growth rate of commercial broiler chickens. The result is animals that reach market weight in a relatively short time. However, this often affects the health of the limbs, when such rapid growth is associated with skeletal disorders, when ideal bone development does not occur due to the rapid increase in body weight. While the time it takes to gain slaughter, weight has steadily decreased over the past few years, the time it takes for healthy bone development remains more or less the same. Therefore, studies carried out from the point of view of a better understanding of a relatively little-explored area such as the genetic architecture of bones, can bring insights that can be used in poultry breeding. One of the relatively important signaling pathways for bone metabolism is the RANK/RANKL/OPG and Wnt pathways. Our study is focused on the search for polymorphisms within selected genes (TNFRSF11A and WISP1) of these pathways that might show associations with the traits we are monitoring. Testing was done on 43 broilers, namely fast-growing Ross 308, Cobb 500, and slow-growing Hubbard M22BxJA87A broilers. A total of thirteen polymorphisms were found, three of which were synonymous and five in an intron. Among the found polymorphisms, no one showed associations with the traits we were monitoring.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

40201 - Animal and dairy science; (Animal biotechnology to be 4.4)

Project

—

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Microbiology, Biotechnology and Food Sciences

ISSN

1338-5178

e-ISSN

1338-5178

Volume of the periodical

15

Issue of the periodical within the volume

1

Country of publishing house

SK - SLOVAKIA

Number of pages

5

Pages from-to

"e11735"

UT code for WoS article

001511219200001

EID of the result in the Scopus database

2-s2.0-105012897222