Association of increased erythrocyte osmotic resistance with haematological and histopathological findings in dogs with congenital extrahepatic portosystemic shunt

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F13%3A43872677" target="_blank" >RIV/62157124:16170/13:43872677 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.2754/avb201382040393" target="_blank" >http://dx.doi.org/10.2754/avb201382040393</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2754/avb201382040393" target="_blank" >10.2754/avb201382040393</a>

Result language

angličtina

Original language name

Association of increased erythrocyte osmotic resistance with haematological and histopathological findings in dogs with congenital extrahepatic portosystemic shunt

Original language description

The aim of the study was to investigate changes in erythrocyte osmotic resistance in relation to haematological and histological changes in dogs with a congenital portosystemic shunt. Osmotic fragility tests with complete blood counts and liver histological examinations were performed in 12 dogs with single extrahepatic portosystemic shunt confirmed by surgical exploration. Laboratory results were compared with those from 30 healthy dogs. Dogs with portosystemic shunt had a significantly increased erythrocyte osmotic resistance (P { 0.01) with 5%, 50% and 90% haemolysis corresponding to 0.45%, 0.35% and 0.30% NaCl solution, respectively. Statistical analyses revealed no correlation between haematological indicators and the osmotic fragility test results. Increased osmotic resistance was significantly associated with hepatic lipogranulomas. Based on these results, dogs with a congenital portosystemic shunt have a significantly increased erythrocyte osmotic resistance suggesting impaired

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

GJ - Diseases and animal vermin, veterinary medicine

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Acta veterinaria Brno

ISSN

0001-7213

e-ISSN

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Volume of the periodical

82

Issue of the periodical within the volume

4

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

6

Pages from-to

393-398

UT code for WoS article

000331597000008

EID of the result in the Scopus database

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