Tissue factor, plasminogen and plasminogen activator inhibitor in dogs with gastric dilatation and volvulus.

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F14%3A43873283" target="_blank" >RIV/62157124:16170/14:43873283 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Tissue factor, plasminogen and plasminogen activator inhibitor in dogs with gastric dilatation and volvulus.
Original language description
Gastric dilatation and volvulus syndrome (GDV) is frequently associated with alteration in coagulation and fibrinolytic system leading to disseminated intravascular coagulation (DIC). However, trigger of DIC in these dogs is not known yet. Aim of this study was to compare level of tissue factor (TF), plasminogen (P) and plasminogen activator inhibitor (PAI) in dogs with GDV and healthy controls and to correlate severity of haemostatic imbalance with these parameters. Platelet count (PLT), prothrombin time (PT), activated partial thromboplastin time (aPTT), level of fibrinogen (FBG) and D-dimers, TF, P and PAI were measured in 19 dogs with GDV and 12 healthy dogs. In dogs with GDV, alteration of each PLT, PT, aPTT, FBG and D-dimers was scored by 1 point. Levels of TF, P and PAI were compared between GDV and control dogs using Mann-Whitney U test, correlation of score and TF, P and PAI was performed using Spearman correlation coefficient. Significant difference between control dogs and d
Czech name
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Czech description
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Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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