Analysis of cell cycle related gene expression in Myb deficient mandible - a pilot study

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F21%3A43879342" target="_blank" >RIV/62157124:16170/21:43879342 - isvavai.cz</a>
Result on the web
—
DOI - Digital Object Identifier
—

Result language
angličtina
Original language name
Analysis of cell cycle related gene expression in Myb deficient mandible - a pilot study
Original language description
Myb is a transcription factor well known as a cell cycle regulator. Its possible impact on cell cycle regulation during mandibular bone formation was examined using Myb deficient mice. PCR Array revealed genes affected by Myb: Ccna1 (CyclinA1), Ccne1 (CyclinE1), Cdkn2a (Cyclin-dependent kinase inhibitor 2A), E2f2 (Transcription factor E2F2), Gpr132 (G protein-coupled receptor 132) and Slfn1 (Schlafen1). Our previous studies confirmed increased expression of Myb in the forming mandibular bone. The present pilot study further indicates possible mechanisms of Myb functions in osteogenesis and provides a background for more detailed analyses.
Czech name
—
Czech description
—

Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)