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A novel Ion AMpliSeq-based typing method of Toxoplasma gondii reveals aN ExCELLENT typing resolution among European type II strains

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F22%3A43880143" target="_blank" >RIV/62157124:16170/22:43880143 - isvavai.cz</a>

  • Alternative codes found

    RIV/62157124:16810/22:43880143

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    A novel Ion AMpliSeq-based typing method of Toxoplasma gondii reveals aN ExCELLENT typing resolution among European type II strains

  • Original language description

    Toxoplasma gondii has a clonal population structure in Europe. The currently available typing method, based on 15 microsatellite regions, has a limited ability to discriminate between different type II strains. We therefore aimed to establish a next-generation sequencing (NGS)-based method with a higher typing resolution.Methods: T. gondii isolates were collected from different parts of Europe and assessed by whole genome sequencing (WGS). Highly polymorphic regions (HPRs) were identified. After confirmation by Sanger sequencing, 18 HPRs were used to design a primer panel suitable to establish an Ion AmpliSeq-based typing tool.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

  • OECD FORD branch

    40301 - Veterinary science

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2022

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů