Plasmid-mediated colistin resistance among human clinical Enterobacteriaceae isolates: surveillance in the Czech Republic, 2017-2019

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F20%3A43878770" target="_blank" >RIV/62157124:16270/20:43878770 - isvavai.cz</a>
Alternative codes found
RIV/62157124:16810/20:43878770
Result on the web
<a href="https://fvhe.vfu.cz/files/upload/media-verejnost/sborniky-z-konferenci/KMVP%202020_sborn%C3%ADk.pdf" target="_blank" >https://fvhe.vfu.cz/files/upload/media-verejnost/sborniky-z-konferenci/KMVP%202020_sborn%C3%ADk.pdf</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Plasmid-mediated colistin resistance among human clinical Enterobacteriaceae isolates: surveillance in the Czech Republic, 2017-2019
Original language description
The prevalence of colistin resistance has increased rapidly among Enterobacteriaceae. National surveillance of plasmid-mediated colistin resistance started in the Czech Republic in 2017. The aim of this study was to determine the prevalence and characteristics of isolates with mcr genes from human clinical samples. In all strains, resistance to colistin was evaluated by determination of the minimal inhibitory concentration (MIC) by the broth microdilution method. Of 704 strains analysed, twenty-five (3.6%) were positive for mcr-1 and one (0.14%) for mcr-4. Four plasmid groups (ColE10, IncX4, IncHI2, IncI2) with mcr-1 gene were identified and epidemic mcr-1-carrying IncX4 plasmid predominated among our collection of clinical samples.
Czech name
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Czech description
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Project
<a href="/en/project/NV18-09-00605" target="_blank" >NV18-09-00605: Enterobacteriaceae resistant to carbapenems and colistin: One-Health approach in addressing human and non-human sources of emerging antimicrobial resistance mechanisms</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
Sborník příspěvků XXII. konference mladých vědeckých pracovníků s mezinárodní účastí
ISBN
978-80-7305-846-3
ISSN
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e-ISSN
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Number of pages
3
Pages from-to
103-105
Publisher name
Veterinární a farmaceutická univerzita Brno
Place of publication
Brno
Event location
Brno
Event date
May 20, 2020
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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