Efficacy of the intranasal application of azaperone for sedation in weaned piglets

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F23%3A43881041" target="_blank" >RIV/62157124:16270/23:43881041 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/23:00131023 RIV/62157124:16170/23:43881041

Result on the web

<a href="https://doi.org/10.17221/21/2023-VETMED" target="_blank" >https://doi.org/10.17221/21/2023-VETMED</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.17221/21/2023-VETMED" target="_blank" >10.17221/21/2023-VETMED</a>

Result language

angličtina

Original language name

Efficacy of the intranasal application of azaperone for sedation in weaned piglets

Original language description

The aim of the study was to compare the efficacy of the intranasal and parenteral administration of azaperone in order to achieve pig sedation. A total of 32 weaned piglets divided into 4 groups (8 piglets in each group) were used. Group A was injected intramuscularly (i.m.) with azaperone (Stresnil (R), 40 mg/ml inj.; Elanco Animal Health) at a dose of 2 mg/kg of body weight (b.w.). Group B received a dose of 2 mg/kg b.w. of azaperone intranasally. Group C was given azaperone intranasally at a dose of 4 mg/kg b.w. Group D was given 1 ml of saline intranasally and served as the control group. The response to the defined stimulus (a blunt blow of a metal rod into a metal edge of a pen), the degree of salivation, movement level, body temperature and serum azaperone concentration were included in the trial. We found that in order to induce an adequate level of sedation comparable to the standard method of application, i.e., 2 mg/kg b.w. i.m., the intranasal administration of azaperone at a dose of 4 mg/kg body weight is required.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

40301 - Veterinary science

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Veterinární medicína

ISSN

0375-8427

e-ISSN

1805-9392

Volume of the periodical

68

Issue of the periodical within the volume

4

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

7

Pages from-to

145-151

UT code for WoS article

000981543900001

EID of the result in the Scopus database

—