The effects of buccal administration of azaperone on the sedation level and biochemical variables of weaned piglets

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F21%3A43879828" target="_blank" >RIV/62157124:16170/21:43879828 - isvavai.cz</a>

Alternative codes found

RIV/62157124:16270/21:43879828

Result on the web

<a href="https://actavet.vfu.cz/media/pdf/actavet_2021090010047.pdf" target="_blank" >https://actavet.vfu.cz/media/pdf/actavet_2021090010047.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2754/avb202190010047" target="_blank" >10.2754/avb202190010047</a>

Result language

angličtina

Original language name

The effects of buccal administration of azaperone on the sedation level and biochemical variables of weaned piglets

Original language description

The aim of the study was to compare the efficacy of buccal and parenteral administration of azaperone in order to achieve pig sedation. The type of study was prospective randomized and double blinded. A total of 40 weaned piglets were divided into 4 groups (10 each) and monitored. Group A was injected intramuscularly (i.m.) with azaperone (Stresnil (R), 40 mg/ml inj., Elanco Animal Health) at a dose of 2 mg/kg body weight (b.w.). Group B (control) was given 1 ml of saline buccally. Group C received a dose of 2 mg/kg b.w. of azaperone buccally. Group D was given azaperone buccally at a dose of 4 mg/kg b.w. The response to defined stimulus (a blunt blow of a metal rod into the metal edge of the pen), degree of salivation, movement level, blood plasma azaperone concentration, and the haematological and biochemical variables were included in the study. We found that the buccal administration of azaperone is effective, however, a dose of 4 mg/kg b.w. is required to induce a sedation level comparable to the standard 2 mg/kg b.w. i.m. administration.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

40301 - Veterinary science

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Acta veterinaria Brno

ISSN

0001-7213

e-ISSN

—

Volume of the periodical

90

Issue of the periodical within the volume

1

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

10

Pages from-to

47-56

UT code for WoS article

000654628800006

EID of the result in the Scopus database

2-s2.0-85104735374