EVALUATION OF SORPTIVE PROPERTIES OF VARIOUS CARRIERS AND COATING MATERIALS FOR LIQUISOLID SYSTEMS
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16370%2F15%3A43873549" target="_blank" >RIV/62157124:16370/15:43873549 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
EVALUATION OF SORPTIVE PROPERTIES OF VARIOUS CARRIERS AND COATING MATERIALS FOR LIQUISOLID SYSTEMS
Original language description
The basic principle of liquisolid systems formulation lies in the conversion of the drug in a liquid state into an apparently dry, free-flowing and readily compressible powder by its blending (or spraying) with specific carriers and coating materials. The selection of the most suitable carrier and coating material depends especially on their values of flowable liquid retention potential (Phi), which is defined as the maximum mass of liquid that can be retained per unit mass of powder material, while maintaining an acceptable flowability. The presented work focused on the determination of the maximum amount of propylene glycol (PG), which can be retained by several selected carriers and coating materials while maintaining acceptable flow properties of the liquisolid powder blend. Granulated forms of magnesium aluminometasilicates (Neusilin (R) US2 and Neusilin (R) NS2N), dibasic calcium phosphate (Fujicalin (R)) and microcrystalline cellulose (Avicel (R) PH 101) were tested due to their
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Acta Poloniae Pharmaceutica - Drug Research
ISSN
0001-6837
e-ISSN
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Volume of the periodical
72
Issue of the periodical within the volume
3
Country of publishing house
PL - POLAND
Number of pages
11
Pages from-to
539-549
UT code for WoS article
000363440000014
EID of the result in the Scopus database
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