Assessment of plasma protein C activity in dogs with portosystemic shunt
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16810%2F23%3A43880995" target="_blank" >RIV/62157124:16810/23:43880995 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14310/23:00133639 RIV/62157124:16170/23:43880995
Result on the web
<a href="https://actavet.vfu.cz/media/pdf/actavet_2023092030289.pdf" target="_blank" >https://actavet.vfu.cz/media/pdf/actavet_2023092030289.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2754/avb202392030289" target="_blank" >10.2754/avb202392030289</a>
Alternative languages
Result language
angličtina
Original language name
Assessment of plasma protein C activity in dogs with portosystemic shunt
Original language description
Portosystemic shunt (PSS) is a vascular disease that can be treated by various surgical techniques. Current veterinary studies are evaluating new prognostic markers in dogs with PSS. This study aims at evaluating the prognostic value of plasma protein C activity in dogs (n = 34) with PSS treated surgically using an ameroid constrictor. Plasma protein C activity was measured in the following time periods: preoperatively (T1), 2 days after surgery (T2), 8 weeks after surgery (T3) and > 6 months after surgery (T4). There was a significant increase in plasma protein C activity between T1/T2 and T3/T4 (P < 0.001). There was no significant relationship between the plasma protein C activity and sex (P = 0.676), age (P = 0.172), breed (P = 0.573), type of clinical signs (neurological P = 0.993; gastrointestinal P = 0.924; urological P = 0.385) and type of portosystemic shunt (P = 0.516), except for dogs with a caval type of extrahepatic PSS termination that had significant lower plasma protein C activity values compared to dogs with a diaphragmatic type of extrahepatic PSS (P = 0.031). No significant relationship was found between plasma protein C activity and the probability of the dog’s death (P = 0.334) or the dog’s clinical outcome (P = 0.960). Although not a prognostic factor, protein C activity is a laboratory marker that is useful for the diagnosis of PSS in dogs and can also be helpful in the postoperative monitoring.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
40301 - Veterinary science
Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Acta veterinaria Brno
ISSN
0001-7213
e-ISSN
1801-7576
Volume of the periodical
92
Issue of the periodical within the volume
3
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
13
Pages from-to
289-301
UT code for WoS article
001153359000009
EID of the result in the Scopus database
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