Traditional Ayurvedic and herbal remedies for Alzheimer's disease: from bench to bedside

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62690094%3A18470%2F19%3A50015601" target="_blank" >RIV/62690094:18470/19:50015601 - isvavai.cz</a>

Result on the web

<a href="https://www.tandfonline.com/doi/abs/10.1080/14737175.2019.1596803?journalCode=iern20" target="_blank" >https://www.tandfonline.com/doi/abs/10.1080/14737175.2019.1596803?journalCode=iern20</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/14737175.2019.1596803" target="_blank" >10.1080/14737175.2019.1596803</a>

Result language

angličtina

Original language name

Traditional Ayurvedic and herbal remedies for Alzheimer's disease: from bench to bedside

Original language description

Introduction: Alzheimer&apos;s disease (AD) is a progressive, neurodegenerative disorder prevalent worldwide among elderly populations. Owing to limited efficacy, side effects, and poor patient compliance for current rationally designed therapies, options are being searched from alternate therapies such as Indian (Ayurvedic), Chinese, or other traditional systems. Areas covered: Following a comprehensive literature search, the authors provide a review encompassing: (1) pathophysiological changes involved in AD, (2) Ayurvedic holistic approach and herbal medicines to manage dementia and AD, and (3) traditional plants and their phytoconstituents effective in AD with description of possible mechanism of action. Expert opinion: Traditional remedies could be adjunct therapeutic options to allay wide-ranging pathological cascades of AD. Ayurveda offers a holistic approach of treatment along with a list of nootropic herbs and formulations that are the rich sources of antioxidants, anti-amyloidogenic, neuroprotective, adaptogenic, anti-inflammatory, and immunomodulatory compounds that are found to modulate neuroendocrine-immune activities, enhance memory, intellect, rejuvenate brain functions, and improve quality of life. A strong knowledge base of traditional systems coupled with contemporary science may provide new functional leads for age-associated neurodegenerative disorders at preventive, promotive, and curative levels, and evolution of new drug therapies and development processes, though further research is needed.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30104 - Pharmacology and pharmacy

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

EXPERT REVIEW OF NEUROTHERAPEUTICS

ISSN

1473-7175

e-ISSN

—

Volume of the periodical

19

Issue of the periodical within the volume

5

Country of publishing house

GB - UNITED KINGDOM

Number of pages

16

Pages from-to

359-374

UT code for WoS article

000466274800001

EID of the result in the Scopus database

2-s2.0-85066118534