Tetraspanins in mammalian reproduction: spermatozoa, oocytes and embryos
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62690094%3A18470%2F20%3A50020155" target="_blank" >RIV/62690094:18470/20:50020155 - isvavai.cz</a>
Alternative codes found
RIV/86652036:_____/20:00534677 RIV/60460709:41210/20:81701 RIV/00216208:11310/20:10418183
Result on the web
<a href="https://link.springer.com/article/10.1007/s00430-020-00676-0" target="_blank" >https://link.springer.com/article/10.1007/s00430-020-00676-0</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00430-020-00676-0" target="_blank" >10.1007/s00430-020-00676-0</a>
Alternative languages
Result language
angličtina
Original language name
Tetraspanins in mammalian reproduction: spermatozoa, oocytes and embryos
Original language description
It is known that tetraspanin proteins are involved in many physiological somatic cell mechanisms. Additionally, research has indicated they also have a role in various infectious diseases and cancers. This review focuses on the molecular interactions underlying the tetraspanin web formation in gametes. Primarily, tetraspanins act in the reproductive tract as organizers of membrane complexes, which include the proteins involved in the contact and association of sperm and oocyte membranes. In addition, recent data shows that tetraspanins are likely to be involved in these processes in a complex way. In mammalian fertilization, an important role is attributed to CD molecules belonging to the tetraspanin superfamily, particularly CD9, CD81, CD151, and also CD63; mostly as part of extracellular vesicles, the significance of which and their potential in reproduction is being intensively investigated. In this article, we reviewed the existing knowledge regarding the expression of tetraspanins CD9, CD81, CD151, and CD63 in mammalian spermatozoa, oocytes, and embryos and their involvement in reproductive processes, including pathological events.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30102 - Immunology
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
MEDICAL MICROBIOLOGY AND IMMUNOLOGY
ISSN
0300-8584
e-ISSN
1432-1831
Volume of the periodical
209
Issue of the periodical within the volume
4
Country of publishing house
US - UNITED STATES
Number of pages
19
Pages from-to
407-425
UT code for WoS article
000533800300001
EID of the result in the Scopus database
2-s2.0-85084855927