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Tetraspanins in mammalian reproduction: spermatozoa, oocytes and embryos

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F86652036%3A_____%2F20%3A00534677" target="_blank" >RIV/86652036:_____/20:00534677 - isvavai.cz</a>

  • Alternative codes found

    RIV/60460709:41210/20:81701 RIV/00216208:11310/20:10418183 RIV/62690094:18470/20:50020155

  • Result on the web

    <a href="https://scholar.google.com/scholar_lookup?author=J%20Jankovicova&atitle=Tetraspanins%20in%20mammalian%20reproduction:%20spermatozoa,%20oocytes%20and%20embryos&publication_year=2020&hl=en&journal=MEDICAL%20MICROBIOLOGY%20AND%20IMMUNOLOGY&volume=209&issue=4&pages=407-425&issn=0300-8584&doi=10.1007/s00430-020-00676-0&pmid=32424440" target="_blank" >https://scholar.google.com/scholar_lookup?author=J%20Jankovicova&atitle=Tetraspanins%20in%20mammalian%20reproduction:%20spermatozoa,%20oocytes%20and%20embryos&publication_year=2020&hl=en&journal=MEDICAL%20MICROBIOLOGY%20AND%20IMMUNOLOGY&volume=209&issue=4&pages=407-425&issn=0300-8584&doi=10.1007/s00430-020-00676-0&pmid=32424440</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/s00430-020-00676-0" target="_blank" >10.1007/s00430-020-00676-0</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Tetraspanins in mammalian reproduction: spermatozoa, oocytes and embryos

  • Original language description

    It is known that tetraspanin proteins are involved in many physiological somatic cell mechanisms. Additionally, research has indicated they also have a role in various infectious diseases and cancers. This review focuses on the molecular interactions underlying the tetraspanin web formation in gametes. Primarily, tetraspanins act in the reproductive tract as organizers of membrane complexes, which include the proteins involved in the contact and association of sperm and oocyte membranes. In addition, recent data shows that tetraspanins are likely to be involved in these processes in a complex way. In mammalian fertilization, an important role is attributed to CD molecules belonging to the tetraspanin superfamily, particularly CD9, CD81, CD151, and also CD63, mostly as part of extracellular vesicles, the significance of which and their potential in reproduction is being intensively investigated. In this article, we reviewed the existing knowledge regarding the expression of tetraspanins CD9, CD81, CD151, and CD63 in mammalian spermatozoa, oocytes, and embryos and their involvement in reproductive processes, including pathological events.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10606 - Microbiology

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2020

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Medical Microbiology and Immunology

  • ISSN

    0300-8584

  • e-ISSN

  • Volume of the periodical

    209

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    18

  • Pages from-to

    407-425

  • UT code for WoS article

    000533800300001

  • EID of the result in the Scopus database

    2-s2.0-85084855927