Progress on the detoxification of aflatoxin B1 using natural anti-oxidants
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62690094%3A18470%2F22%3A50019434" target="_blank" >RIV/62690094:18470/22:50019434 - isvavai.cz</a>
Alternative codes found
RIV/00179906:_____/22:10451183
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0278691522006159?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0278691522006159?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.fct.2022.113417" target="_blank" >10.1016/j.fct.2022.113417</a>
Alternative languages
Result language
angličtina
Original language name
Progress on the detoxification of aflatoxin B1 using natural anti-oxidants
Original language description
Aflatoxins are toxic secondary metabolites produced by Aspergillus fungi. The most toxic among them is Aflatoxin B1 (AFB1) which is known to have genotoxic, immunotoxic, teratogenic, carcinogenic, and mutagenic toxic effects (amongst others). The mechanisms responsible for its toxicity include the induction of oxidative stress, cytotoxicity, and DNAdamage. Studies have found that natural anti-oxidants can reduce the damage that AFB1 inflicts on the body by alleviating oxidative stress and inhibiting the biotransformation of AFB1. Therefore, this review outlines the latest progress in research on the use of natural anti-oxidants as antidotes to aflatoxin poisoning and their detoxification mechanisms. It also considers the problems that may possibly arise from their use and their application prospects. Our aim is to provide a useful reference for the prevention and treatment of AFB1 poisoning. © 2022
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30108 - Toxicology
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Food and Chemical Toxicology
ISSN
0278-6915
e-ISSN
1873-6351
Volume of the periodical
169
Issue of the periodical within the volume
November
Country of publishing house
GB - UNITED KINGDOM
Number of pages
10
Pages from-to
"Article number: 113417"
UT code for WoS article
000876186700004
EID of the result in the Scopus database
2-s2.0-85137778166