CLL cells cumulate genetic aberrations prior to the first therapy even in outwardly inactive disease phase

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F19%3A00069166" target="_blank" >RIV/65269705:_____/19:00069166 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14740/19:00109079
Result on the web
<a href="https://www.nature.com/articles/s41375-018-0255-1.pdf" target="_blank" >https://www.nature.com/articles/s41375-018-0255-1.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/s41375-018-0255-1" target="_blank" >10.1038/s41375-018-0255-1</a>

Result language
angličtina
Original language name
CLL cells cumulate genetic aberrations prior to the first therapy even in outwardly inactive disease phase
Original language description
Over the past few years, several large-scale studies using next-generation sequencing (NGS) of whole-genomes (WGS) and whole-exomes (WES) have defined the mutational landscape of chronic lymphocytic leukemia (CLL). NGS studies have also revealed the clonal heterogeneity in CLL and showed that clonal evolution contributes to the variability in clinical course among CLL patients.
Czech name
—
Czech description
—

Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30204 - Oncology

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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