The combination of endoluminal radiofrequency ablation and metal stent implantation for the treatment of malignant biliary stenosis-Randomized study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F21%3A00074907" target="_blank" >RIV/65269705:_____/21:00074907 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/21:00122392

Result on the web

<a href="https://www.ejradiology.com/article/S0720-048X(21)00311-9/fulltext" target="_blank" >https://www.ejradiology.com/article/S0720-048X(21)00311-9/fulltext</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ejrad.2021.109830" target="_blank" >10.1016/j.ejrad.2021.109830</a>

Result language

angličtina

Original language name

The combination of endoluminal radiofrequency ablation and metal stent implantation for the treatment of malignant biliary stenosis-Randomized study

Original language description

Purpose: To analyse whether endobiliary radiofrequency ablation prior metal stent insertion in malignant biliary stenosis show improved survival or stent patency. Methods: 76 patients with histologically proven malignant biliary stenosis have been enrolled in a prospective, randomized study. In control arm, 40 patients underwent self-expandable metal stent insertion. In experimental arm, the endoluminal ablation with a bipolar radiofrequency catheter was performed immediately before stent insertion. A subgroup analysis of cholangiocarcinoma was performed (22 vs 21 patients). The objective of the study was to determine the rate of complications, duration of the stent patency and the survival of patients (Kaplan-Meier analysis). Results: No major complications related to the stent insertion and the endoluminal ablation were found. The mean primary stent patency was 5.2 (95% CI 0.7-12.8) vs 4.8 months (95% CI 0.8-18.2) months (p = 0.79) in control and experimental group, respectively, in the subgroup analysis with cholangiocarcinoma 4.5 (95% CI 0.8-10.3) and 9.6 (95% CI 5.2-11.2) months (p = 0.029). The median survival since the insertion of the stent was 6.8 (95 %CI 3.0-10.6) vs 5.2 (95 %CI 2.4-7.9) months (p = 0.495) and since the initial drainage 9.8 (95 %CI 6.9-12.7) vs 9.1 (95 %CI 5.4-12.7) months (p = 0.720) in the control and experimental arm. Conclusion: Endobiliary radiofrequency ablation prior metal stent insertion showed increased patency rate only in patients with cholangiocarcinoma, on the other hand, no improvement in survival was demonstrated in this randomized clinical study.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30224 - Radiology, nuclear medicine and medical imaging

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

European journal of radiology

ISSN

0720-048X

e-ISSN

—

Volume of the periodical

142

Issue of the periodical within the volume

SEP

Country of publishing house

IE - IRELAND

Number of pages

7

Pages from-to

109830

UT code for WoS article

000687783200001

EID of the result in the Scopus database

2-s2.0-85109038627