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Expression and subcellular redistribution of proteinkinase C isoforms in chronically hypoxic rat heart: effects of inhibitors

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F07%3A00324221" target="_blank" >RIV/67985823:_____/07:00324221 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Expression and subcellular redistribution of proteinkinase C isoforms in chronically hypoxic rat heart: effects of inhibitors

  • Original language description

    The aim of study was to analyzed acute effects of proteinkinase C (PKC) inhibitors on the expression and subcellular localization of PKC isoforms ? and ? in normoxic and chronically hypoxic rat hearts. The results of study are in line with negative effects of PKC inhibitors on the increased ischemic tolerance of chronically hypoxic hearts and support the view that PKC plays a role in this long-term cardioprotective mechanism

  • Czech name

    Exprese a subcelulární distribuce izoforem protein kinázy C v chronicky hypoxickém myokardu: vliv inhibitorů

  • Czech description

    Cílem studie bylo zjistit, jak ovlivní akutní podání inhibitorů proteinkinázy C (PKC) expresi a subcelulární lokalizaci izoforem ? a ? PKC v srdci chronicky hypoxických potkanů. Výsledky studie potvrdily negativní účinek PKC inhibitorů na kardioprotektivní účinek chronické hypoxic a prokázaly klíčové postavení PKC v tomto mechanismu

Classification

  • Type

    C - Chapter in a specialist book

  • CEP classification

    FA - Cardiovascular diseases including cardio-surgery

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA305%2F07%2F0875" target="_blank" >GA305/07/0875: Cardioprotective mechanisms of chronic intermittent and sustained hypoxia: role of reoxygenation.</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2007

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Book/collection name

    Nitric oxide signaling pathways

  • ISBN

    978-80-8071-094-1

  • Number of pages of the result

    6

  • Pages from-to

  • Number of pages of the book

    145

  • Publisher name

    Advent-Orion

  • Place of publication

    Bratislava

  • UT code for WoS chapter