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The effects of pertussis toxin-treatment on integrated vasoactive response of vascular system in spontaneously hypertensive rats

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F08%3A00307022" target="_blank" >RIV/67985823:_____/08:00307022 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    The effects of pertussis toxin-treatment on integrated vasoactive response of vascular system in spontaneously hypertensive rats

  • Original language description

    After pretreatment of SHR with PTX the hypotensive response to ACh was reduced in comparison to Wistar rats. Moreover, NA-induced pressor response was considerably decreased after PTX pretreatment compared to untreated SHR. The results suggested that theactivation of PTX-sensitive inhibitory Gi proteins is involved in the regulation of integrative vasoactive responses in SHR

  • Czech name

    Efekt pertussis toxinu na integrovanou vazoaktivní odpověď cévního systému potkanů se spontánní hypertenzí

  • Czech description

    Hypotenzivní odpověď na ACh byla snížena u SHR potkanů ovlivněných pertussis toxinem (PTX). Podobně, tlaková odpověď na noradrenalin byla snížena u potkanů ovlivněných PTX. Výsledky ukazují, že aktivace inhibičních Gi proteinů senzitivních na PTX se podílí na regulaci integrované vazoaktivní odpovědi u SHR

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FA - Cardiovascular diseases including cardio-surgery

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/1M0510" target="_blank" >1M0510: Centre for cardiovascular research</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2008

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Physiological Research

  • ISSN

    0862-8408

  • e-ISSN

  • Volume of the periodical

    57

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    3

  • Pages from-to

    137-139

  • UT code for WoS article

  • EID of the result in the Scopus database