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Controversial action of positive modulator of subtype 7 of metabotropic glutamate receptors AMN082 on cortical epileptic afterdischarges in immature rats

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F09%3A00331449" target="_blank" >RIV/67985823:_____/09:00331449 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11130/09:5360

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Controversial action of positive modulator of subtype 7 of metabotropic glutamate receptors AMN082 on cortical epileptic afterdischarges in immature rats

  • Original language description

    Positive allosteric modulator of mGluR7 AMN082 augmented cortical epileptic afterdischarges characterized by spike-and-wave rhythm in the EEG in all three studied age groups (rats 12, 18 and 25 days old). On the contrary, the second type of afterdischarges indicating spread of epileptic activity into limbic system in 25-day-old rats is suppressed by AMN082

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FH - Neurology, neuro-surgery, nuero-sciences

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA305%2F06%2F1188" target="_blank" >GA305/06/1188: Effects of drugs influencing metabotropic glutamate receptors in immature laboratory rats</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2009

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    European Journal of Pharmacology

  • ISSN

    0014-2999

  • e-ISSN

  • Volume of the periodical

    623

  • Issue of the periodical within the volume

    1-3

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    4

  • Pages from-to

  • UT code for WoS article

    271853500006

  • EID of the result in the Scopus database