High efficiency of ROS production by glycerophosphate dehydrogenase in mammalian mitochondria
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F09%3A00338638" target="_blank" >RIV/67985823:_____/09:00338638 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
High efficiency of ROS production by glycerophosphate dehydrogenase in mammalian mitochondria
Original language description
A high rates of mGPDH-dependent ROS production were observed in liver, heart and brain mitochondria treated with antimycin. When related to activity of mGPDH, 3-39-fold higher ROS production was found in contrast to succinate dehydrogenase- or NADH dehydrogenase-dependent ROS production. It was also 22-66 higher compared to that in BAT. Our results demonstrate high efficiency of mGPDH-dependent ROS production localized to the dehydrogenase + CoQ and complex III, in mammalian mitochondria with a low content of mGPDH and suggest its endogenous inhibition in BAT
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2009
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Archives of Biochemistry and Biophysics
ISSN
0003-9861
e-ISSN
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Volume of the periodical
481
Issue of the periodical within the volume
1
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
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UT code for WoS article
262540500004
EID of the result in the Scopus database
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