All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

Protons stabilize the closed conformation of gain-of-function mutants of the TRPV1 channel

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F13%3A00394052" target="_blank" >RIV/67985823:_____/13:00394052 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.bbamcr.2012.11.017" target="_blank" >http://dx.doi.org/10.1016/j.bbamcr.2012.11.017</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.bbamcr.2012.11.017" target="_blank" >10.1016/j.bbamcr.2012.11.017</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Protons stabilize the closed conformation of gain-of-function mutants of the TRPV1 channel

  • Original language description

    The vanilloid transient receptor potential channel TRPV1 is a molecular integrator of noxious stimuli, including capsaicin, heat and protons. To explore the function of S1 in TRPV1, we used tryptophan-scanning mutagenesis and characterized the responsesto capsaicin and protons. We propose that the S1 domain contains a functionally important region that may be specifically involved in TRPV1 channel gating, and thus be important for the energetic coupling between S1-S4 sensor activation and gate opening

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    ED - Physiology

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2013

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Biochimica Et Biophysica Acta-Molecular Cell Research

  • ISSN

    0167-4889

  • e-ISSN

  • Volume of the periodical

    1833

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    9

  • Pages from-to

    520-528

  • UT code for WoS article

    000315308100010

  • EID of the result in the Scopus database