Entrainment of Spontaneously Hypertensive Rat Fibroblasts by Temperature Cycles

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F13%3A00397537" target="_blank" >RIV/67985823:_____/13:00397537 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1371/journal.pone.0077010" target="_blank" >http://dx.doi.org/10.1371/journal.pone.0077010</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1371/journal.pone.0077010" target="_blank" >10.1371/journal.pone.0077010</a>

Result language
angličtina
Original language name
Entrainment of Spontaneously Hypertensive Rat Fibroblasts by Temperature Cycles
Original language description
We showed that two consecutive square-wave temperature cycles with amplitudes of 2.5°C are with similar efficiency able to restart damped oscillations and entrain the circadian clock in fibroblasts derived from both spontaneously hypertensive rat and control Wistar rat. We described phase response curves to temperature cycles for fibroblast clock from both strains and concluded that despite slight resistance of SHR cells to temperature entrainment, the overall effect is too weak to be responsible for SHR circadian phenotype in vivo
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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