Fluconazole treatment hyperpolarizes the plasma membrane of Candida cells

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F13%3A00397981" target="_blank" >RIV/67985823:_____/13:00397981 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.3109/13693786.2013.779038" target="_blank" >http://dx.doi.org/10.3109/13693786.2013.779038</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3109/13693786.2013.779038" target="_blank" >10.3109/13693786.2013.779038</a>

Result language
angličtina
Original language name
Fluconazole treatment hyperpolarizes the plasma membrane of Candida cells
Original language description
Five pathogenic Candida species were compared in terms of their osmotolerance, tolerance to toxic sodium and lithium cations, and resistance to fluconazole. we show that the fluconazole treatment of growing cells of all five species results in a substantial hyperpolarization of their plasma membranes, which is responsible for an increased non-specific transport of toxic alkali metal cations and other cationic drugs
Czech name
—
Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EE - Microbiology, virology
OECD FORD branch
—

Project
<a href="/en/project/GAP302%2F12%2F1151" target="_blank" >GAP302/12/1151: Intracellular pH and alkali-metal-cation homeostasis in Candida virulence and pathogenicity</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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