MK-801 impairs cognitive coordination on a rotating arena (Carousel) and contextual specificity of hippocampal immediate-early gene expression in a rat model of psychosis

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F14%3A00427701" target="_blank" >RIV/67985823:_____/14:00427701 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.3389/fnbeh.2014.00075" target="_blank" >http://dx.doi.org/10.3389/fnbeh.2014.00075</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3389/fnbeh.2014.00075" target="_blank" >10.3389/fnbeh.2014.00075</a>

Result language
angličtina
Original language name
MK-801 impairs cognitive coordination on a rotating arena (Carousel) and contextual specificity of hippocampal immediate-early gene expression in a rat model of psychosis
Original language description
This original study shows that administration of MK-801, a non-competitive blocker of NMDA receptors, in an acute animal model of schizophrenia, impairs cognitive coordination on the rotating arena (Carousel) and contextual specificity if IEGs expressionin the CA1 region of the hippocampus. The study employed variants of place avoidance task on Carousel and molecular imaging of IEGs
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Project
<a href="/en/project/GPP303%2F10%2FP191" target="_blank" >GPP303/10/P191: The role and the mechanism of segregation of information in the rat hippocampus in behavioural discrimination and in animal model of schizophrenia.</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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