Cardioprotective adaptation of rats to intermittent hypobaric hypoxia is accompanied by the increased association of hexokinase with mitochondria

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F15%3A00454176" target="_blank" >RIV/67985823:_____/15:00454176 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1152/japplphysiol.01035.2014" target="_blank" >http://dx.doi.org/10.1152/japplphysiol.01035.2014</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1152/japplphysiol.01035.2014" target="_blank" >10.1152/japplphysiol.01035.2014</a>

Result language
angličtina
Original language name
Cardioprotective adaptation of rats to intermittent hypobaric hypoxia is accompanied by the increased association of hexokinase with mitochondria
Original language description
We found significantly elevated expression of HK isoforms (HK1 and HK2) in left ventricular myocardium of rats adapted to severe intermittent hypoxia. Hypoxia also increased the total HK activity and the association of HK isoforms with mitochondria in both ventricles. These findings suggest that HK may contribute to the cardioprotective phenotype induced by adaptation to intermittent hypoxia
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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