Microstructural Analysis of Collagenous Structures in Relapsed Clubfoot Tissue

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F23%3A00570504" target="_blank" >RIV/67985823:_____/23:00570504 - isvavai.cz</a>

Alternative codes found

RIV/68407700:21220/23:00371932 RIV/00216224:14740/23:00133612 RIV/00216208:11130/23:10457945 RIV/00216208:11110/23:10457945 and 2 more

Result on the web

<a href="https://doi.org/10.1093/micmic/ozac012" target="_blank" >https://doi.org/10.1093/micmic/ozac012</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/micmic/ozac012" target="_blank" >10.1093/micmic/ozac012</a>

Result language

angličtina

Original language name

Microstructural Analysis of Collagenous Structures in Relapsed Clubfoot Tissue

Original language description

Talipes equinovarus congenitus (clubfoot) is frequently defined as a stiff, contracted deformity, but few studies have described the tissue from the point of view of the extracellular matrix, and none have quantified its mechanical properties. Several researchers have observed that clubfoot exhibits signs of fibrosis in the medial side of the deformity that are absent in the lateral side. Our study aims to quantify the differences between the medial and lateral side tissue obtained from relapsed clubfoot during surgery in terms of the morphological and mechanical properties of the tissue. Combining methods of optical and atomic force microscopy, our study revealed that the medial side has a higher Young’s modulus, contains more collagen and less adipose tissue and that the collagen fibers propagate at a higher frequency of the crimp pattern after surgical dissection of the tissue. Our study offers a multi-correlative approach that thoroughly investigates the relapsed clubfoot tissue.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30211 - Orthopaedics

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Microscopy and Microanalysis

ISSN

1431-9276

e-ISSN

1435-8115

Volume of the periodical

29

Issue of the periodical within the volume

1

Country of publishing house

US - UNITED STATES

Number of pages

8

Pages from-to

265-272

UT code for WoS article

001033590800026

EID of the result in the Scopus database

2-s2.0-85153729727