Current Approaches to Wound Repair in Burns: How far we Have Come From Cover to Close? A Narrative Review

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F24%3A00583345" target="_blank" >RIV/67985823:_____/24:00583345 - isvavai.cz</a>

Alternative codes found

RIV/61388963:_____/24:00583345 RIV/00216208:11130/24:10475576 RIV/46747885:24510/24:00012334 RIV/00216208:11120/24:43926622 and 2 more

Result on the web

<a href="https://doi.org/10.1016/j.jss.2023.12.043" target="_blank" >https://doi.org/10.1016/j.jss.2023.12.043</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jss.2023.12.043" target="_blank" >10.1016/j.jss.2023.12.043</a>

Result language

angličtina

Original language name

Current Approaches to Wound Repair in Burns: How far we Have Come From Cover to Close? A Narrative Review

Original language description

Burn injuries are a significant global health concern, with more than 11 million people requiring medical intervention each year and approximately 180,000 deaths annually. Despite progress in health and social care, burn injuries continue to result in socioeconomic burdens for victims and their families. The management of severe burn injuries involves preventing and treating burn shock and promoting skin repair through a two-step procedure of covering and closing the wound. Currently, split-thickness/full-thickness skin autografts are the gold standard for permanent skin substitution. However, deep burns treated with split-thickness skin autografts may contract, leading to functional and appearance issues. Conversely, defects treated with full-thickness skin autografts often result in more satisfactory function and appearance. The development of tissue-engineered dermal templates has further expanded the scope of wound repair, providing scar reductive and regenerative properties that have extended their use to reconstructive surgical interventions. Although their interactions with the wound microenvironment are not fully understood, these templates have shown potential in local infection control. This narrative review discusses the current state of wound repair in burn injuries, focusing on the progress made from wound cover to wound closure and local infection control. Advancements in technology and therapies hold promise for improving the outcomes for burn injury patients. Understanding the underlying mechanisms of wound repair and tissue regeneration may provide new insights for developing more effective treatments in the future.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10601 - Cell biology

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Surgical Research

ISSN

0022-4804

e-ISSN

1095-8673

Volume of the periodical

296

Issue of the periodical within the volume

April

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

21

Pages from-to

383-403

UT code for WoS article

001182164100001

EID of the result in the Scopus database

2-s2.0-85185179580