Mucin Aggregation from a Rod-like Meso-Scale Model

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985858%3A_____%2F15%3A00445895" target="_blank" >RIV/67985858:_____/15:00445895 - isvavai.cz</a>
Alternative codes found
RIV/44555601:13440/15:43886693
Result on the web
<a href="http://dx.doi.org/10.1080/00268976.2015.1023750" target="_blank" >http://dx.doi.org/10.1080/00268976.2015.1023750</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/00268976.2015.1023750" target="_blank" >10.1080/00268976.2015.1023750</a>

Result language
angličtina
Original language name
Mucin Aggregation from a Rod-like Meso-Scale Model
Original language description
Dissipative particle dynamics, a meso?scale particle-based model, was used to study the aggregation of mucins in aqueous solutions. Concentration, strength of the mucin?water interactions, as well as the effects of size, shape, and composition of the model molecules were studied. Model proteins were represented as rod-like objects formed by coarse-grained beads. In the first model, only one type of beads formed the mucin. It was found that all the surfaces were available to form aggregates and the conformation of the aggregates was a function of the strength of the mucin?water interaction. With this model, the number of aggregates was unaffected by the initial position of the mucins in the simulation box, except for the lowest mucin concentration. In amore refined mucin model, two kinds of beads were used in the molecule in order to represent the existence of cysteine-like terminal groups in the actual molecule. With this new scheme, aggregation took place by the interaction of the te
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CF - Physical chemistry and theoretical chemistry
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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