Effect of hyaluronidase and PEG chain conjugation on the biologic and antitumour activity of RNase A
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F04%3A00100592" target="_blank" >RIV/67985904:_____/04:00100592 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Effect of hyaluronidase and PEG chain conjugation on the biologic and antitumour activity of RNase A
Original language description
Subcutaneous application of bovine RNase A conjugated to HYase (bovine hyaluronidase), polyethylene glycol(PEG)and HYase+PEG resulted in a marker reduction of the width of the spermatogenic layers of the mouse testes. The number of sperms in caput epididymidis was significantly desreased in mice injected with conjugated RNase A
Czech name
Působení ribonukleasy A konjugované hyaluronidasou a PEG na biologické a protinádorové aktivity
Czech description
Subkutánní aplikace bovinní RNase A kojugované s Hyase (bovidní hyaluronidasa,polyethylen glykolem /PEG) snižoval aspermatogenní efekt. Melanomový nádor rostoucí na athymických myších však byl podstatně zmenšen
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA523%2F01%2F0114" target="_blank" >GA523/01/0114: Antitumor effects of bovine seminal ribonuclease on animal and human melanoblastoma, neuroblastoma, meduloblastoma and glioblastoma</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2004
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Controlled Release
ISSN
0168-3659
e-ISSN
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Volume of the periodical
94
Issue of the periodical within the volume
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Country of publishing house
US - UNITED STATES
Number of pages
10
Pages from-to
401-410
UT code for WoS article
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EID of the result in the Scopus database
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