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The antitumour effect of ribonucleases and antiangiogenins on human tumours in nude mice

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F13%3A00427541" target="_blank" >RIV/61389013:_____/13:00427541 - isvavai.cz</a>

  • Alternative codes found

    RIV/67985904:_____/13:00427541

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    The antitumour effect of ribonucleases and antiangiogenins on human tumours in nude mice

  • Original language description

    Bovine seminal ribonuclease (BS-RNase) and bovine pancreatic ribonuclease (RNase A) have potent antitumour activity. In this study, the antitumour effect of selected low-toxic antiangiogenins of natural origin and bovine ribonucleases conjugated with polyethylene glycol (PEG) was tested. The antiangiogenins were selected according their toxicity. The antitumour activity of PEGylated BS-RNase and RNase A was enhanced when injected together with antiangiogenins into the athymic nude mice bearing human pancreatic tumours and human melanoma C-32 tumours.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CD - Macromolecular chemistry

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2013

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Trends in Cancer Research

  • ISSN

    0973-1040

  • e-ISSN

  • Volume of the periodical

    9

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    IN - INDIA

  • Number of pages

    9

  • Pages from-to

    43-51

  • UT code for WoS article

  • EID of the result in the Scopus database