SGK1 is essential for meiotic resumption in mammalian oocytes

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F22%3A00558029" target="_blank" >RIV/67985904:_____/22:00558029 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11310/22:10453206
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0171933522000139?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0171933522000139?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.ejcb.2022.151210" target="_blank" >10.1016/j.ejcb.2022.151210</a>

Result language
angličtina
Original language name
SGK1 is essential for meiotic resumption in mammalian oocytes
Original language description
In mammalian females, oocytes are stored in the ovary and meiosis is arrested at the diplotene stage of prophase I. When females reach puberty oocytes are selectively recruited in cycles to grow, overcome the meiotic arrest, complete the first meiotic division and become mature (ready for fertilization). At a molecular level, the master regulator of prophase I arrest and meiotic resumption is the maturation-promoting factor (MPF) complex, formed by the active form of cyclin dependent kinase 1 (CDK1) and Cyclin B1. However, we still do not have complete information regarding the factors implicated in MPF activation.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10605 - Developmental biology

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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