Influence of viscous Rhodella grisea (Rhodophyceae) proteoglycan on chemically induced cough reflex

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985939%3A_____%2F11%3A00369361" target="_blank" >RIV/67985939:_____/11:00369361 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.ijbiomac.2011.08.029" target="_blank" >http://dx.doi.org/10.1016/j.ijbiomac.2011.08.029</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.ijbiomac.2011.08.029" target="_blank" >10.1016/j.ijbiomac.2011.08.029</a>

Result language
angličtina
Original language name
Influence of viscous Rhodella grisea (Rhodophyceae) proteoglycan on chemically induced cough reflex
Original language description
An algal extracellular biopolymer (over 8.5 105 Da) composed of carbohydrates (52%) and protein (13%) has been isolated from a red alga Rhodella grisea growing in natural conditions by concentration of water medium, alcohol precipitation, dialysis and freeze-drying. This mucilagineous biopolymer contained xylose and its 3-O- and 4-O-methyl derivatives (63%), galactose (12%), glucuronic acid (11?12%), glucose (5%), rhamnose (4%), fucose (3?4%) and low content of others accompaning sugars. When tested onthe citric acid-induced cough and reactivity of airways smooth muscle in vivo in the test system guinea pigs, this biopolymer assigned a significant cough suppressing effect. The reactivity of airways smooth muscle was not affected indicating that expectoration effect was not suppressed by biopolymer application, which is important from the pharmacological point of view.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EF - Botany
OECD FORD branch
—

Project
<a href="/en/project/1M0571" target="_blank" >1M0571: Bioindication and revitalization of toxic and antropogenic substrates and water sources: application of cyano bacteria, algae, soil bacteria and symbiotic fungi</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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