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Influence of viscous Rhodella grisea (Rhodophyceae) proteoglycan on chemically induced cough reflex

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985939%3A_____%2F11%3A00369361" target="_blank" >RIV/67985939:_____/11:00369361 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.ijbiomac.2011.08.029" target="_blank" >http://dx.doi.org/10.1016/j.ijbiomac.2011.08.029</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.ijbiomac.2011.08.029" target="_blank" >10.1016/j.ijbiomac.2011.08.029</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Influence of viscous Rhodella grisea (Rhodophyceae) proteoglycan on chemically induced cough reflex

  • Original language description

    An algal extracellular biopolymer (over 8.5 105 Da) composed of carbohydrates (52%) and protein (13%) has been isolated from a red alga Rhodella grisea growing in natural conditions by concentration of water medium, alcohol precipitation, dialysis and freeze-drying. This mucilagineous biopolymer contained xylose and its 3-O- and 4-O-methyl derivatives (63%), galactose (12%), glucuronic acid (11?12%), glucose (5%), rhamnose (4%), fucose (3?4%) and low content of others accompaning sugars. When tested onthe citric acid-induced cough and reactivity of airways smooth muscle in vivo in the test system guinea pigs, this biopolymer assigned a significant cough suppressing effect. The reactivity of airways smooth muscle was not affected indicating that expectoration effect was not suppressed by biopolymer application, which is important from the pharmacological point of view.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EF - Botany

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/1M0571" target="_blank" >1M0571: Bioindication and revitalization of toxic and antropogenic substrates and water sources: application of cyano bacteria, algae, soil bacteria and symbiotic fungi</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    International Journal of Biological Macromolecules

  • ISSN

    0141-8130

  • e-ISSN

  • Volume of the periodical

    49

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    5

  • Pages from-to

    1046-1050

  • UT code for WoS article

    000296937200028

  • EID of the result in the Scopus database