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DNA interactions of new cytotoxic tetrafunctional dinuclear platinum complex trans,trans-[{PtCl2(NH3)}2(piperazine)]

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F07%3A00082644" target="_blank" >RIV/68081707:_____/07:00082644 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    DNA interactions of new cytotoxic tetrafunctional dinuclear platinum complex trans,trans-[{PtCl2(NH3)}2(piperazine)]

  • Original language description

    A new tetrafunctional dinuclear platinum complex trans,trans-[{PtCl2(NH3)}2(piperazin)] with sterically rigid linking group was designed, synthesized and characterized. It has been shown that this complex or its analogues could be used as a tool for studies of DNA properties and their interactions or as a potential antitumor agent.

  • Czech name

    Interakce DNA s novým cytotoxickým tetrafunkčním dvojjaderným komplexem platiny trans,trans-[{PtCl2(NH3)}2(piperazine)

  • Czech description

    Byl navržen, syntetizován a charakterizován nový tetrafunkční dinukleární komplex trans,trans-[{PtCl2(NH3)}2(piperazin)] se stericky rigidním můstkem. Bylo ukázáno, že tento komplex nebo jeho analogy by mohly být využity jako nástroje pro studium vlastností a interakcí DNA nebo jako potenciální protinádorové léčivo.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    BO - Biophysics

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2007

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Biochemical Pharmacology

  • ISSN

    0006-2952

  • e-ISSN

  • Volume of the periodical

    73

  • Issue of the periodical within the volume

    12

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    14

  • Pages from-to

    1887-1900

  • UT code for WoS article

  • EID of the result in the Scopus database