Influence of pyridine versus piperidine ligands on the chemical, DNA binding and cytotoxic properties of light activated trans,trans,trans-[Pt(N3)2(OH)2(NH3)(L)]

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F11%3A00368775" target="_blank" >RIV/68081707:_____/11:00368775 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.jinorgbio.2011.01.003" target="_blank" >http://dx.doi.org/10.1016/j.jinorgbio.2011.01.003</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jinorgbio.2011.01.003" target="_blank" >10.1016/j.jinorgbio.2011.01.003</a>

Result language
angličtina
Original language name
Influence of pyridine versus piperidine ligands on the chemical, DNA binding and cytotoxic properties of light activated trans,trans,trans-[Pt(N3)2(OH)2(NH3)(L)]
Original language description
The photocytotoxicity and photobiochemical properties of the new complex trans,trans,trans-[Pt(N3)2(OH)2(NH3)(piperidine)] are compared with its analogue containing the less basic and less lipophilic ligand pyridine. The results indicate that the piperidine complex has a more rapid rate of light activation to cytotoxic species but in other cellular and biochemical aspects its behavior is similar to that of pyridine analogue.
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
BO - Biophysics
OECD FORD branch
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)