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Thermodynamic and mechanistic insights into translesion DNA synthesis catalyzed by Y-family DNA polymerase across a bulky double-base lesion of an antitumor platinum drug

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F12%3A00386041" target="_blank" >RIV/68081707:_____/12:00386041 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1002/chem.201202117" target="_blank" >http://dx.doi.org/10.1002/chem.201202117</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1002/chem.201202117" target="_blank" >10.1002/chem.201202117</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Thermodynamic and mechanistic insights into translesion DNA synthesis catalyzed by Y-family DNA polymerase across a bulky double-base lesion of an antitumor platinum drug

  • Original language description

    It has been determined how the Y-family translesion DNA polymerase eta processes a DNA double-base lesion derived from 1,2-GG intrastrand cross-links of a new antitumor PtII complex containing a bulky carrier ligand, namely [PtCl2(cis-1,4-dach)] (dach=diaminocyclohexane).

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    BO - Biophysics

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Chemistry - A European Journal

  • ISSN

    0947-6539

  • e-ISSN

  • Volume of the periodical

    18

  • Issue of the periodical within the volume

    48

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    10

  • Pages from-to

    15439-15448

  • UT code for WoS article

    000311306700029

  • EID of the result in the Scopus database