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Composite 5-methylations of cytosines modulate i-motif stability in a sequence-specific manner: Implications for DNA nanotechnology and epigenetic regulation of plant telomeric DNA

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F20%3A00536135" target="_blank" >RIV/68081707:_____/20:00536135 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216224:14740/20:00115829

  • Result on the web

    <a href="https://www.sciencedirect.com/science/article/pii/S030441652030163X?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S030441652030163X?via%3Dihub</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.bbagen.2020.129651" target="_blank" >10.1016/j.bbagen.2020.129651</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Composite 5-methylations of cytosines modulate i-motif stability in a sequence-specific manner: Implications for DNA nanotechnology and epigenetic regulation of plant telomeric DNA

  • Original language description

    Background: The i-motif is a tetrameric DNA structure based on the formation of hemiprotonated cytosinecytosine (C+.C) base pairs. i-motifs are widely used in nanotechnology. In biological systems, i-motifs are involved in gene regulation and in control of genome integrity. In vivo, the i-motif forming sequences are subjects of epigenetic modifications, particularly 5-cytosine methylation. In plants, natively occurring methylation patterns lead to a complex network of C+.C, C-5m(+).C and C-5m(+).C-5m base-pairs in the i-motif stem. The impact of complex methylation patterns (CMPs) on i-motif formation propensity is currently unknown.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10608 - Biochemistry and molecular biology

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2020

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Biochimica et Biophysica Acta. General Subjects

  • ISSN

    0304-4165

  • e-ISSN

  • Volume of the periodical

    1864

  • Issue of the periodical within the volume

    9

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    9

  • Pages from-to

    129651

  • UT code for WoS article

    000541151100006

  • EID of the result in the Scopus database

    2-s2.0-85086044891