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Fast blood plasma separation device for point-of-care applications

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081715%3A_____%2F18%3A00486643" target="_blank" >RIV/68081715:_____/18:00486643 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216224:14310/18:00111646

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.talanta.2018.02.004" target="_blank" >http://dx.doi.org/10.1016/j.talanta.2018.02.004</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.talanta.2018.02.004" target="_blank" >10.1016/j.talanta.2018.02.004</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Fast blood plasma separation device for point-of-care applications

  • Original language description

    In this work, a simple device for extremely fast separation of blood plasma from diluted whole blood was developed.nThe device accommodates an asymmetric polysulfone membrane/supporting membrane sandwich thatnallows collection of 10μL blood plasma into a narrow glass capillary in less than 10s. The composition of diluentnsolution was optimized in order to achieve maximum recoveries for selected metabolites of alcohol intoxication.n5% solution of [tris(hydroxymethyl)methylamino] propanesulfonic acid provided recoveries of formate, oxalatenand glycolate close to 100% and only moderate erythrocyte lysis. Both charged and uncharged compounds fromnthe whole blood samples can be analyzed in the separated blood plasma by capillary electrophoresis with contactlessnconductometric detection and spectrophotometry, respectively. The developed device might find widenapplication in on-site testing and point-of-care analysis, when only microliter volumes of whole blood are available.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10406 - Analytical chemistry

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Talanta

  • ISSN

    0039-9140

  • e-ISSN

  • Volume of the periodical

    183

  • Issue of the periodical within the volume

    JUN

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    6

  • Pages from-to

    55-60

  • UT code for WoS article

    000430645800008

  • EID of the result in the Scopus database

    2-s2.0-85042222134