Electrophoretic Deposition and Characterization ofnFunctional Coatings Based on an AntibacterialnGallium (III)‐Chitosan Complex

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081723%3A_____%2F20%3A00524683" target="_blank" >RIV/68081723:_____/20:00524683 - isvavai.cz</a>

Result on the web

<a href="https://www.mdpi.com/2079-6412/10/5/483" target="_blank" >https://www.mdpi.com/2079-6412/10/5/483</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/coatings10050483" target="_blank" >10.3390/coatings10050483</a>

Result language

angličtina

Original language name

Electrophoretic Deposition and Characterization ofnFunctional Coatings Based on an AntibacterialnGallium (III)‐Chitosan Complex

Original language description

Despite their broad biomedical applications in orthopedics and dentistry, metallicnimplants are still associated with failures due to their lack of surface biofunctionality, leading tonprosthesis‐related microbial infections. In order to address this issue, the current study focuses onnthe fabrication and characterization of a novel type of antibacterial coating based on gallium (III)‐nchitosan (Ga (III)‐CS) complex layers deposited on metallic substrates via electrophoretic depositionn(EPD). Aiming for the production of homogeneous and monophasic coatings, a two step‐procedurenwas applied: the first step involved the synthesis of the Ga (III)‐CS complex, followed by EPD fromnsuitable solutions in an acetic acid–aqueous solvent. The influence of Ga (III) concentration on thenstability of the suspensions was evaluated in terms of zeta potential. Fourier transform infraredn(FTIR) and energy dispersive X‐ray (EDX) spectroscopic analyses indicated the chelation of CS withnGa (III) within the coatings, while scanning electron microscopy (SEM) confirmed that no additionalnmetallic gallium deposited during EPD. Furthermore, the results demonstrated that the wettability,nmechanical properties, swelling ability, and enzymatic degradation of the coatings were affected bynthe quantity of Ga (III) ions. Colony forming unit (CFU) tests showed a strong synergistic effectnbetween CS and Ga (III) in inhibiting Escherichia coli strain growth compared to control CS samples.nAn in vitro study with MG‐63 cells showed that Ga (III)‐containing coatings were not toxic after 24 h ofnincubation.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

20506 - Coating and films

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Coatings

ISSN

2079-6412

e-ISSN

—

Volume of the periodical

10

Issue of the periodical within the volume

5

Country of publishing house

CH - SWITZERLAND

Number of pages

20

Pages from-to

483

UT code for WoS article

000541770900061

EID of the result in the Scopus database

2-s2.0-85086678138