Left Ventricular Myocardial Septal Pacing in Close Proximity to LBB Does Not Prolong the Duration of the Left Ventricular Lateral Wall Depolarization Compared to LBB Pacing
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081731%3A_____%2F21%3A00551968" target="_blank" >RIV/68081731:_____/21:00551968 - isvavai.cz</a>
Alternative codes found
RIV/00159816:_____/21:00075888 RIV/00216208:11120/21:43922673 RIV/00216305:26220/21:PU142472 RIV/00064173:_____/21:N0000039
Result on the web
<a href="https://www.frontiersin.org/articles/10.3389/fcvm.2021.787414/full" target="_blank" >https://www.frontiersin.org/articles/10.3389/fcvm.2021.787414/full</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3389/fcvm.2021.787414" target="_blank" >10.3389/fcvm.2021.787414</a>
Alternative languages
Result language
angličtina
Original language name
Left Ventricular Myocardial Septal Pacing in Close Proximity to LBB Does Not Prolong the Duration of the Left Ventricular Lateral Wall Depolarization Compared to LBB Pacing
Original language description
Background: Three different ventricular capture types are observed during left bundle branch pacing (LBBp). They are selective LBB pacing (sLBBp), non-selective LBB pacing (nsLBBp), and myocardial left septal pacing transiting from nsLBBp while decreasing the pacing output (LVSP). Study aimed to compare differences in ventricular depolarization between these captures using ultra-high-frequency electrocardiography (UHF-ECG).Methods: Using decremental pacing voltage output, we identified and studied nsLBBp, sLBBp, and LVSP in patients with bradycardia. Timing of ventricular activations in precordial leads was displayed using UHF-ECGs, and electrical dyssynchrony (e-DYS) was calculated as the difference between the first and last activation. The durations of local depolarizations (Vd) were determined as the width of the UHF-QRS complex at 50% of its amplitude.Results: In 57 consecutive patients, data were collected during nsLBBp (n = 57), LVSP (n = 34), and sLBBp (n = 23). Interventricular dyssynchrony (e-DYS) was significantly lower during LVSP16 ms (-21, 11), than nsLBBp24 ms (-28, 20) and sLBBp31 ms (-36, 25). LVSP had the same V1d-V8d as nsLBBp and sLBBp except for V3d, which during LVSP was shorter than sLBBp, the mean difference9 ms (-16, 1), p = 0.01. LVSP caused less interventricular dyssynchrony and the same or better local depolarization durations than nsLBBp and sLBBp irrespective of QRS morphology during spontaneous rhythm or paced QRS axis.Conclusions: In patients with bradycardia, LVSP in close proximity to LBB resulted in better interventricular synchrony than nsLBBp and sLBBp and did not significantly prolong depolarization of the left ventricular lateral wall.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Frontiers in Cardiovascular Medicine
ISSN
2297-055X
e-ISSN
2297-055X
Volume of the periodical
8
Issue of the periodical within the volume
07 December
Country of publishing house
CH - SWITZERLAND
Number of pages
10
Pages from-to
787414
UT code for WoS article
000741843100001
EID of the result in the Scopus database
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