Ultra-high-frequency ECG volumetric and negative derivative epicardial ventricular electrical activation pattern
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081731%3A_____%2F24%3A00585087" target="_blank" >RIV/68081731:_____/24:00585087 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/24:00136429 RIV/00216208:11120/24:43926829 RIV/00216305:26220/24:PU151149 RIV/00064173:_____/24:43926829 RIV/00159816:_____/24:00081527
Result on the web
<a href="https://www.nature.com/articles/s41598-024-55789-w" target="_blank" >https://www.nature.com/articles/s41598-024-55789-w</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/s41598-024-55789-w" target="_blank" >10.1038/s41598-024-55789-w</a>
Alternative languages
Result language
angličtina
Original language name
Ultra-high-frequency ECG volumetric and negative derivative epicardial ventricular electrical activation pattern
Original language description
From precordial ECG leads, the conventional determination of the negative derivative of the QRS complex (ND-ECG) assesses epicardial activation. Recently we showed that ultra-high-frequency electrocardiography (UHF-ECG) determines the activation of a larger volume of the ventricular wall. We aimed to combine these two methods to investigate the potential of volumetric and epicardial ventricular activation assessment and thereby determine the transmural activation sequence. We retrospectively analyzed 390 ECG records divided into three groups-healthy subjects with normal ECG, left bundle branch block (LBBB), and right bundle branch block (RBBB) patients. Then we created UHF-ECG and ND-ECG-derived depolarization maps and computed interventricular electrical dyssynchrony. Characteristic spatio-temporal differences were found between the volumetric UHF-ECG activation patterns and epicardial ND-ECG in the Normal, LBBB, and RBBB groups, despite the overall high correlations between both methods. Interventricular electrical dyssynchrony values assessed by the ND-ECG were consistently larger than values computed by the UHF-ECG method. Noninvasively obtained UHF-ECG and ND-ECG analyses describe different ventricular dyssynchrony and the general course of ventricular depolarization. Combining both methods based on standard 12-lead ECG electrode positions allows for a more detailed analysis of volumetric and epicardial ventricular electrical activation, including the assessment of the depolarization wave direction propagation in ventricles.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
20601 - Medical engineering
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Scientific Reports
ISSN
2045-2322
e-ISSN
2045-2322
Volume of the periodical
14
Issue of the periodical within the volume
1
Country of publishing house
US - UNITED STATES
Number of pages
11
Pages from-to
5681
UT code for WoS article
001185083700069
EID of the result in the Scopus database
2-s2.0-85186926921