LVSP and LBBP Result in Similar or Improved LV Synchrony and Hemodynamics Compared to BVP

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081731%3A_____%2F24%3A00588405" target="_blank" >RIV/68081731:_____/24:00588405 - isvavai.cz</a>

Alternative codes found

RIV/00023001:_____/24:00084989 RIV/00216208:11120/24:43927087 RIV/00064173:_____/24:43927087

Result on the web

<a href="https://www.sciencedirect.com/science/article/pii/S2405500X24003487" target="_blank" >https://www.sciencedirect.com/science/article/pii/S2405500X24003487</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jacep.2024.04.022" target="_blank" >10.1016/j.jacep.2024.04.022</a>

Result language

angličtina

Original language name

LVSP and LBBP Result in Similar or Improved LV Synchrony and Hemodynamics Compared to BVP

Original language description

Background: The effect of left ventricular septal myocardial pacing (LVSP) and left bundle branch pacing (LBBP) on ventricular synchrony and left ventricular (LV) hemodynamic status is poorly understood. Objectives: The aim of this study was to investigate the impact of LVSP and LBBP vs biventricular pacing (BVP) on ventricular electrical synchrony and hemodynamic status in cardiac resynchronization therapy patients. Methods: In cardiac resynchronization therapy candidates with LV conduction disease, ventricular synchrony was assessed by measuring QRS duration (QRSd) and using ultra-high-frequency electrocardiography. LV electrical dyssynchrony was assessed as the difference between the first activation in leads V1 1 to V8 8 to the last from leads V4 4 to V8. 8 . LV hemodynamic status was estimated using invasive systolic blood pressure measurement during multiple transitions between LBBP, LVSP, and BVP. Results: A total of 35 patients with a mean LV ejection fraction of 29% and a mean QRSd of 168 f 24 ms were included. Thirteen had ischemic cardiomyopathy. QRSd during BVP, LVSP, and LBBP was the same, but LBBP provided shorter LV electrical dyssynchrony than BVP (-10 ms, 95% CI:-16 to-4 ms, P = 0.001), the difference between LVSP and BVP was not significant (-5 ms, 95% CI:-12 to 1 ms, P = 0.10). LBBP was associated with higher systolic blood pressure than BVP (4%, 95% CI: 2%-5%, P < 0.001), whereas LVSP was not (1%, 95% CI: 0%-2%, P = 0.10). Hemodynamic differences during LBBP and LVSP vs BVP were more pronounced in nonischemic than ischemic patients. Conclusions: Ultra-high-frequency electrocardiography allowed the documentation of differences in LV synchrony between LBBP, LVSP, and BVP, which were not observed by measuring QRSd. LVSP provided the same LV synchrony and hemodynamic status as BVP, while LBBP was better than BVP in both. (c) 2024 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30201 - Cardiac and Cardiovascular systems

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

JACC-Clinical Electrophysiology

ISSN

2405-500X

e-ISSN

2405-5018

Volume of the periodical

10

Issue of the periodical within the volume

7

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

11

Pages from-to

1722-1732

UT code for WoS article

001282699400001

EID of the result in the Scopus database

2-s2.0-85195079398