Measurement of Cerebral Blood Flow by ASL MRI in Rat Models of Psychopathology and Psychopharmacological Interventions
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081731%3A_____%2F25%3A00639967" target="_blank" >RIV/68081731:_____/25:00639967 - isvavai.cz</a>
Result on the web
<a href="https://link.springer.com/rwe/10.1007/978-3-031-73368-0_166" target="_blank" >https://link.springer.com/rwe/10.1007/978-3-031-73368-0_166</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-3-031-73368-0_166" target="_blank" >10.1007/978-3-031-73368-0_166</a>
Alternative languages
Result language
angličtina
Original language name
Measurement of Cerebral Blood Flow by ASL MRI in Rat Models of Psychopathology and Psychopharmacological Interventions
Original language description
This chapter explores the use of arterial spin labeling (ASL) magnetic resonance imaging (MRI) to measure cerebral blood flow (CBF) in rat models of psychopathology and psychopharmacological interventions. It provides a comprehensive overview of ASL as a non-invasive technique that uses blood as an endogenous tracer, offering high-quality perfusion images without the need for contrast agents. The chapter emphasizes ASL’s utility in assessing microvascular CBF changes in various experimental conditions, including pharmacological manipulations and rodent models of psychiatric disorders. It discusses critical aspects of experimental design, including the choice of animal models, strain selection, and control of variables such as stress and circadian rhythms. The chapter also highlights the translational potential of ASL in neuropsychiatric research, particularly in understanding disease mechanisms and evaluating treatment effects. Ultimately, ASL MRI is presented as a valuable tool for preclinical research with significant implications for clinical applications.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
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OECD FORD branch
30104 - Pharmacology and pharmacy
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Handbook of the Biology and Pathology of Mental Disorders
ISBN
978-3-031-73367-3
Number of pages of the result
23
Pages from-to
3353-3375
Number of pages of the book
3457
Publisher name
Springer
Place of publication
Cham
UT code for WoS chapter
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